You are not as charming as you think you are. Stop trying to use your obnoxious laugh to get me to do things for you. I am your assistant. It is my job to do things for you, and your staccato chuckles are not making it any easier. Stop before i punch you in the throat to make that noise go away. Furthermore, charm is not an adequate replacement for competence. Trust me when i tell you that people will like you better if you actually do your job.
Condescension does not help people understand you. It pisses them off. Even the people who are honestly too dumb to know what you are saying will understand that you are being condescending and will hate you forever. Maybe the problem is not the other people. Maybe the problem is you not understanding the various challenges associated with being an adult and having a real job.
Where the hell are you? You have no meetings or appointments today, you just got back from vacation last week, and i have not seen you all day. I need to talk to you to get guidance on my latest assignment. Your employees need to talk to you to check in on their weekly progress. People in other departments need to talk to you so that they can better support our department and improve conditions in their own department. You are a pretty important cog in this machine. When you go AWOL, the entire organization suffers. We need to know where you are. If you want to work from Starbucks, fine. But at least tell me that that's what you're doing. If you are not in this office by noon, i am putting "WANTED" posters all over campus with a picture of you photoshopped to look like Waldo. You have been warned.
Finally, and i cannot stress this enough, you need to do your job. Two months ago, i gave you an invoice. You needed to sign off on the expense and put the correct account number on it. You emailed someone in a different department to ask them which account number to use and she responded that the expense came out of your department, not hers. You then sat on your ass for two months, eating my candy and laughing loudly as you asked me to finish your outstanding Visa statement (i was still waiting on half a dozen receipts from you). Finally, when the neglected expense had become urgent, you went back to the woman from the other department and tried to make her fix your problem. Guess what, asshole? It's still your problem. And if you had taken care of it when you were originally asked to, you wouldn't be in trouble now.
Do. Your. Job.